T-cell adoptive immunotherapy for BK nephropathy in renal transplantation.

Sadia JahanCarla ScuderiLeo FrancisMichelle A NellerSweera RehanPauline CrooksGeorge R AmbalathingalCorey SmithRajiv KhannaGeorge T John

Published in: Transplant infectious disease : an official journal of the Transplantation Society (2020)

We conclude that the T-cell adoptive immunotherapy reduced BKPyV load significantly despite extensive infection, but attendant fibrosis and tubular atrophy led to graft failure. Early intervention with T-cell therapy may prove efficacious in BKPyV nephropathy.

Keyphrases

cell therapy
stem cells
mesenchymal stem cells
randomized controlled trial
high glucose
light emitting