A neutral Cu-based MOF for effective quercetin extraction and conversion from natural onion juice.

We report herein a new microporous neutral three-dimensional (3D) metal-organic framework [Cu 2 (L)(DMF)(H 2 O)]· guest (1· guest ) composed of copper paddle-wheel and flexible tetracarboxylic acid linkers (DMF = N , N -dimethylformamide, H 4 L = tetrakis[(6-carboxynaphthoxy)methyl]methane). Surprisingly, this MOF with neutral cavities can not only extract pure quercetin (QT) but also convert it into Cu-QT during the desorption process. It has been well characterized by UV-vis, IR, ESI-MS and TEM-EDS studies. Moreover, it can efficiently extract natural product QT from fresh QT-rich onion juice and rapidly convert it into Cu-QT with a relatively high conversion rate.