Catalyst-Free Selective Oxidation of Diverse Olefins to Carbonyls in High Yield Enabled by Light under Mild Conditions.
Weiwei YuZhongkui ZhaoPublished in: Organic letters (2019)
The selective oxidation of olefins, in particular, aromatic olefins to carbonyls, is of significance in organic synthesis. In general, stoichiometric toxic oxidants or a high-cost catalyst is required. Herein we report a novel and practical light-enabled protocol for the synthesis of carbonlys in high yield through a catalyst-free oxidation of olefins using H2O2 as a clean oxidant. A broad scope of carbonyls can be synthesized in high yield, and no catalyst or toxic oxidant is required.