Local Transplantation of Mesenchymal Stromal Cells Is Safe and Could Alleviate Kienböck Disease's Complications: A Clinical Trial Study.

Bahareh SadriNarges LabibzadehLida MirmorsaliMarzieh EbrahimiAbolfazl BagherifardLeila ArabNasser AghdamiHoda MadaniAlireza Beheshti MaalShahedeh KarimiSaeed Reza MehrpourMohsen EmadedinAbdolhossein Shahverdi

Published in: Cell journal (2024)

The transplantation of autologous BM-MSCs following lunate core decompression seems to be a safe clinical intervention and may lead to pain relief in patients with Kienböck disease. Furthermore, this procedure may help prevent disease progression during the follow-up period (registration number: NCT02646007).

Keyphrases

clinical trial
bone marrow
cell therapy
randomized controlled trial
minimally invasive
chronic pain
protein kinase
mesenchymal stem cells
pain management
study protocol
open label
phase ii
spinal cord injury
double blind
platelet rich plasma
postoperative pain