Structural MRI measures are associated with fatigue severity and persistence in a large, real-world cohort of people with multiple sclerosis.

Alexandra C SimpsonChen HuEllen M MowryRobert T NaismithKathryn C FitzgeraldBardia Nourbakhsh

Published in: Multiple sclerosis (Houndmills, Basingstoke, England) (2024)

Baseline lesion burden and lower generalized whole-brain volumes were associated with MS fatigue in cross-sectional and longitudinal analyses in a large, real-world cohort of PwMS.

Keyphrases

multiple sclerosis
cross sectional
white matter
sleep quality
magnetic resonance imaging
mass spectrometry
resting state
computed tomography
magnetic resonance
physical activity
risk factors
depressive symptoms
diffusion weighted imaging
functional connectivity
blood brain barrier
cerebral ischemia