Effects of Tegoprazan Versus Esomeprazole on Nighttime Heartburn and Sleep Quality in Gastroesophageal Reflux Disease: A Multicenter Double-blind Randomized Controlled Trial.

Joon Sung Kim Seung In Seo Hyun Yong Jeong Sang Kil LeeAh Rong KimHyun Wook ParkBong Tae KimGeun Seog Song

Published in: Journal of neurogastroenterology and motility (2022)

Tegoprazan may induce faster relief of nighttime heartburn symptoms and may improve sleep disorders associated with nighttime heartburn. Further large-scale studies are required to validate our findings.

Keyphrases

sleep quality
randomized controlled trial
gastroesophageal reflux disease
double blind
depressive symptoms
study protocol
physical activity
clinical trial
placebo controlled
phase iii
case control
phase ii