Prognostic impact of pleural effusion in EGFR-mutant non-small cell lung cancer patients without brain metastasis.
Akihiro YoshimuraTadaaki YamadaTaisuke TsujiRyosuke HamashimaShinsuke ShiotsuTatsuya YubaChieko TakumiJunji UchinoNoriya HiraokaKoichi TakayamaPublished in: Thoracic cancer (2019)
Pleural effusion might be a poor prognosis factor for advanced EGFR-mutant NSCLC patients without brain metastasis treated with first-generation EGFR-tyrosine kinase inhibitors. Further precision medicine according to the metastatic site is required.
Keyphrases
- small cell lung cancer
- poor prognosis
- end stage renal disease
- newly diagnosed
- ejection fraction
- chronic kidney disease
- epidermal growth factor receptor
- long non coding rna
- tyrosine kinase
- peritoneal dialysis
- squamous cell carcinoma
- prognostic factors
- white matter
- multiple sclerosis
- resting state
- brain injury
- blood brain barrier