A Comparison of Gout Flares with the Initiation of Treat-to-Target Allopurinol and Febuxostat: A Post-hoc Analysis of a Randomized Multicenter Trial.
Austin BarryLindsay N HelgetMaria AndrosenkoHongsheng WuBridget KramerJeff A NewcombMary T BrophyAnne Davis-KarimBryant R EnglandRyan FergusonMichael H PillingerTuhina NeogiPaul M PalevskyTony Raymond MerrimanJames R O'DellTed R MikulsPublished in: Arthritis & rheumatology (Hoboken, N.J.) (2024)
These results demonstrate that gout flare risk during the initiation and titration of allopurinol is similar to febuxostat when these agents are administered according to a treat-to-target strategy using gradual ULT dose titration and best practice gout flare prophylaxis.