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Targeted Proteomics Reveals Functional Targets for Early Diabetes Susceptibility in Young Adults.

Ravi V ShahJiawei ZhongLucas MassierKahraman TanriverdiShih-Jen HwangJeffrey HaesslerMatthew NayorShilin ZhaoAndrew S PerryJohn T WilkinsAladdin H ShadyabJo Ann E MansonLisa Warsinger MartinDaniel LevyCharles KooperbergJane E FreedmanMikael RydénVenkatesh L Murthy
Published in: Circulation. Genomic and precision medicine (2024)
A multifaceted discovery effort uniting proteomics, underlying clinical susceptibility phenotypes, and tissue expression patterns may uncover potentially novel functional biomarkers of early diabetes susceptibility in young adults for future mechanistic evaluation.
Keyphrases
  • young adults
  • type diabetes
  • cardiovascular disease
  • mass spectrometry
  • glycemic control
  • poor prognosis
  • small molecule
  • high throughput
  • cancer therapy
  • adipose tissue
  • drug delivery
  • single cell
  • clinical evaluation