Vitamin D Supplementation and Fractures in Adults: A Systematic Umbrella Review of Meta-Analyses of Controlled Trials.

Marlene ChakhtouraDania S BachaCharbel GhariosSara AjjourMariam AssaadYara JabbourFrancesca KahaleAya BassatneStephanie AntounElie A AklRoger BouillonPaul LipsPeter R EbelingGhada El-Hajj Fuleihan

Published in: The Journal of clinical endocrinology and metabolism (2021)

Ca/D reduces the risk of hip and any fractures, possibly driven by findings from institutionalized subjects. Individual participant data meta-analyses of patients on Ca/D with sufficient follow-up period, and subgroup analyses, would unravel determinants for a beneficial response to supplementation.

Keyphrases

meta analyses
systematic review
randomized controlled trial
end stage renal disease
ejection fraction
newly diagnosed
prognostic factors
electronic health record
patient reported outcomes
total hip arthroplasty
big data
study protocol
artificial intelligence
data analysis