High-throughput screening of a collection of known pharmacologically active small compounds for inhibitors of Salmonella invasion and intracellular replication.
Y RidgePaolo LandiniA ThompsonPublished in: Journal of applied microbiology (2018)
The emergence of multidrug-resistant strains of Salmonella poses a considerable and growing worldwide threat to human and animal health. The screening of off-patent chemical libraries represents a potential discovery route for novel antimicrobials.
Keyphrases
- escherichia coli
- multidrug resistant
- listeria monocytogenes
- endothelial cells
- public health
- healthcare
- klebsiella pneumoniae
- small molecule
- gram negative
- mental health
- drug resistant
- human health
- induced pluripotent stem cells
- acinetobacter baumannii
- cell migration
- pluripotent stem cells
- high throughput
- health information
- reactive oxygen species
- health promotion
- social media