The Long Noncoding RNA Blnc1 Protects Against Diet-Induced Obesity by Promoting Mitochondrial Function in White Fat.

Shengjie TangWeifen ZhuFenping ZhengWeiwei GuiWenjing ZhangXihua LinHong Li

Published in: Diabetes, metabolic syndrome and obesity : targets and therapy (2020)

Therefore, eWAT-specific overexpression of Blnc1 improves hepatic steatosis and systemic insulin sensitivity, likely by enhancing mitochondrial biogenesis and function.

Keyphrases

long noncoding rna
insulin resistance
metabolic syndrome
adipose tissue
weight loss
oxidative stress
type diabetes
cell proliferation
high fat diet induced
weight gain
transcription factor
fatty acid
body mass index
skeletal muscle
physical activity