Effects of Platycodin D on Reflux Esophagitis due to Modulation of Antioxidant Defense Systems.

Su-Yeon ChoChang-Hyun SongJi-Eun LeeSeong Hun ChoiSae Kwang Ku Soo-Jin Park

Published in: Evidence-based complementary and alternative medicine : eCAM (2018)

Therapeutic effects of PD on the esophageal and gastric lesions were shown in RE induced rats dose-dependently. The PD pretreatment had significant antioxidant effects with regulation of histamine levels. This study provides useful information regarding the effectiveness of the drug for RE and further novel drug discovery using natural herbal products.

Keyphrases

drug discovery
oxidative stress
anti inflammatory
randomized controlled trial
systematic review
drug induced
high glucose
innate immune
stress induced