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Antiepileptic drug monotherapy for epilepsy in the elderly: A systematic review and network meta-analysis.

Simona LattanziEugen TrinkaCinzia Del GiovaneRaffaele NardoneMauro SilvestriniFrancesco Brigo
Published in: Epilepsia (2019)
Although no significant difference in efficacy was found across treatments, LCM, LTG, and LEV had the highest probability of ranking best for achieving seizure freedom. CBZ-IR and CBZ-CR showed a poor tolerability profile, leading to higher withdrawal rates compared to LEV and VPA.
Keyphrases
  • open label
  • temporal lobe epilepsy
  • middle aged
  • combination therapy
  • community dwelling
  • adverse drug
  • drug induced
  • randomized controlled trial