Treatment outcomes and their determinants of IgG4-related ophthalmic disease: a territory-wide cohort study.
Kenneth Ka Hei LaiEmmy Y M LiRegine Y C ChanWinnie C W ChuAndy C O ChengKaren K W ChanJoyce K Y ChinJeremy S W KwokIda Y F IoNelson K F YipKenneth K W LiWai Ho ChanNai Man LamWilson W K YipAlvin L YoungEdwin ChanCallie K L KoSimon T C KoHunter K L YuenClement Chee Yung ThamChi-Pui PangKelvin Kam-Lung ChongPublished in: The British journal of ophthalmology (2022)
In this cohort, 60% of patients required long-term maintenance oral corticosteroid. Elevated pretreatment serum IgG4 level and Mikulicz syndrome were associated with steroid dependence. Debulking surgery is an alternative for a subgroup of patients with discrete orbital lesions, normal baseline IgG4 level and no Mikulicz syndrome.