131I-3-iodobenzylguanidine or 131I-iobenguane (3-(131I) iodobenzylguanidine or 131I-iobenguane [131I-MIBG]) is a radioactive agent that is specifically accumulated in tumor cells such as pheochromocytoma and neuroblastoma. Due to its cytotoxic beta ray emitted from 131I, it has been developed as an agent for radioisotope therapy and some researchers have reported its effectiveness. In this study, based on the patients' data from previous clinical trials of 131I-MIBG therapy, we evaluated the radiation safety for public exposure caused by radiation emitted from patients who received 131I-MIBG. In results, it was considered that public exposure and medical exposure of visitors and caregivers to the patients were less than their dose limit and dose constraint by complying the current criteria of the release of patients after therapy with 131I.
Keyphrases
- end stage renal disease
- ejection fraction
- clinical trial
- chronic kidney disease
- newly diagnosed
- healthcare
- peritoneal dialysis
- prognostic factors
- randomized controlled trial
- mental health
- systematic review
- stem cells
- palliative care
- mesenchymal stem cells
- open label
- radiation induced
- artificial intelligence
- phase ii