Radiological and pathological predictors of post-operative upstaging of breast ductal carcinoma in situ (DCIS) to invasive ductal carcinoma and lymph-nodes metastasis; a potential algorithm for node surgical de-escalation.

Gianluca VanniMarco PellicciaroMarco MaterazzoMassimiliano BerrettaRosaria MeucciTommaso PerrettaIlaria PortarenaChiara Adriana PistoleseOreste Claudio Buonomo

Published in: Surgical oncology (2024)

We identified pre-operative independent predictors of upstaging to invasive ductal carcinoma. The combined use of different predictors in an algorithm for surgical treatments of DCIS could reduce the numbers of unnecessary SLNB.

Keyphrases

lymph node
machine learning
deep learning
randomized controlled trial
early stage
neoadjuvant chemotherapy
sentinel lymph node