Peripheral Blood Mononuclear Cell Gene Expression in Chronic Obstructive Pulmonary Disease: miRNA and mRNA Regulation.

Lijing Wang Hongjun ZhaoIndu RamanMei YanQiong ChenQuan-Zhen Li

Published in: Journal of inflammation research (2022)

miRNAs and mRNAs are differentially expressed in PBMCs of patients with COPD, compared with normal controls. miRNAs regulate the expression of mRNAs, and thus play a role in the pathogenesis of COPD. Investigating these relationships may provide further insight into the mechanisms of COPD.

Keyphrases

peripheral blood
chronic obstructive pulmonary disease
lung function
gene expression
poor prognosis
dna methylation
binding protein
cell therapy
cystic fibrosis
mesenchymal stem cells
long non coding rna