Age at onset of different pubertal signs in boys and girls and differential DNA methylation at age 10 and 18 years: an epigenome-wide follow-up study.

Su ChenHala RefaeyNandini MukherjeeFarnaz SolatikiaYu JiangS Hasan ArshadSusan EwartJohn W HollowayHongmei ZhangWilfried J J Karmaus

Published in: Human reproduction open (2020)

This work was supported by NIH grants R03HD092776 (Epigenetic characterization of pubertal transitions) and R01AI121226. The 10-year follow-up of this study was funded by National Asthma Campaign, UK (Grant No 364), and the 18-year follow-up by a grant from the National Heart and Blood Institute (R01 HL082925). The authors have no conflicts to report.

Keyphrases

dna methylation
gene expression
genome wide
quality improvement
chronic obstructive pulmonary disease
artificial intelligence
lung function
cross sectional
cystic fibrosis