Mixed aortic valve disease: association with paravalvular leak and reduced survival after transcatheter aortic valve replacement.
Caglayan DemirelMax Paul WinterChristian NitscheSophia KoschatkoCharlotte JantschKatharina MascherbauerKseniya HalavinaGregor HeitzingerCarolina DonaVarius DannenbergGeorg SpinkaMatthias KoschutnikMartin AndreasChristian HengstenbergPhilipp E BartkoPublished in: European heart journal. Cardiovascular Imaging (2024)
MAVD is prevalent among TAVR patients and presents unique challenges, with increased PVR risk and worse outcomes compared with isolated AS. Long-term survival for MAVD patients, not limited to those developing PVR post-TAVR, is compromised. Earlier intervention before the occurrence of structural myocardial damage or surgical valve replacement might be a potential workaround to improve outcomes.
Keyphrases
- aortic valve
- transcatheter aortic valve replacement
- aortic stenosis
- ejection fraction
- transcatheter aortic valve implantation
- aortic valve replacement
- end stage renal disease
- newly diagnosed
- chronic kidney disease
- randomized controlled trial
- prognostic factors
- peritoneal dialysis
- oxidative stress
- metabolic syndrome
- left ventricular
- adipose tissue
- skeletal muscle