Medroxyprogesterone acetate-treated human, primary endometrial epithelial cells reveal unique gene expression signature linked to innate immunity and HIV-1 susceptibility.
Matthew W WoodsMuhammad Atif ZahoorSara DizzellChris P VerschoorCharu KaushicPublished in: American journal of reproductive immunology (New York, N.Y. : 1989) (2017)
The analysis of gene expression profiles provides insights into the effects of sex hormones and MPA on GECs and allows us to posit possible mechanisms of the MPA-mediated increase in HIV-1 acquisition.
Keyphrases
- antiretroviral therapy
- hiv positive
- gene expression
- hiv testing
- hiv infected
- human immunodeficiency virus
- hepatitis c virus
- hiv aids
- men who have sex with men
- genome wide
- endothelial cells
- dna methylation
- copy number
- endometrial cancer
- pluripotent stem cells
- induced pluripotent stem cells
- transcription factor
- genome wide identification