Human Oligodendrocyte Myelination Potential; Relation to Age and Differentiation.

Julia Xiao Xuan LuoQiao-Ling CuiMoein YaqubiJeffery A HallRoy DudleyMyriam SrourNassima AddourHélène JamannCatherine LarochelleManon BlainLuke M HealyJo Anne StrattonJoshua A SonnenTimothy E KennedyJack P Antel

Published in: Annals of neurology (2022)

Our findings identify specific biological pathways relevant to myelination that are differentially enriched in human pediatric and adult OL lineage cells and suggest potential targets for remyelination enhancing therapies. ANN NEUROL 2022;91:178-191.

Keyphrases

endothelial cells
induced pluripotent stem cells
induced apoptosis
pluripotent stem cells
single cell
young adults
neural network