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Association between medication adherence and illness perceptions in atrial fibrillation patients treated with direct oral anticoagulants: An observational cross-sectional pilot study.

Motoyasu MiyazakiAkio NakashimaYoshihiko NakamuraYuya SakamotoKoichi MatsuoMiwa GotoMasanobu UchiyamaKeisuke OkamuraRyoko MitsutakeHidenori UrataHidetoshi KamimuraOsamu Imakyure
Published in: PloS one (2018)
Poor medication adherence to DOACs was strongly associated with a stronger emotional response (i.e. stronger feelings of anger, anxiety, and depression), as well as younger age, the absence of a history of warfarin treatment, and longer DOAC exposure. Further evaluation of the factors associated with medication adherence in AF patients and the development and execution of strategies for improving poor adherence are warranted in the real-world clinical setting.
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