Characterization of left ventricular myocardial sodium-glucose cotransporter 1 expression in patients with end-stage heart failure.

Alex Ali SayourAttila OláhMihály RuppertBálint András BartaEszter Mária HorváthKálmán BenkeMiklós PólosIstván HartyánszkyBéla MerkelyTamás Radovits

Published in: Cardiovascular diabetology (2020)

Myocardial LV SGLT1 is upregulated in patients with HF (except in those with HCM), correlates significantly with parameters of cardiac remodeling (LVEDD) and systolic function (EF), and is downregulated in DCM patients with CRT. The possible role of SGLT1 in LV remodeling needs to be elucidated.

Keyphrases

left ventricular
cardiac resynchronization therapy
hypertrophic cardiomyopathy
heart failure
acute myocardial infarction
left atrial
aortic stenosis
poor prognosis
mitral valve
acute heart failure
binding protein
blood pressure
long non coding rna
atrial fibrillation
aortic valve