Course of body weight before and after the initiation of insulin therapy in type 2 diabetes mellitus: Retrospective inception cohort study (ZODIAC 58).
Mireille A EdensPeter Ruben van DijkEelko HakHenk J G BiloPublished in: Endocrinology, diabetes & metabolism (2020)
Initiation of insulin therapy was independently associated with weight increase; however, overall effect on weight was small and subject to substantial variation. Pre-insulin weight change is identified as a relatively strong inverse determinant of weight change after insulin initiation.