Expression of Collagen (Types I, III, and V), HSP47, MMP-2, and TIMP-1 in Retrobulbar Adipose Tissue of Patients with Thyroid-Associated Orbitopathy.

Hongyang LuoTaixiang Liu Huasheng YangHuijing YeXin Luo

Published in: Journal of ophthalmology (2020)

The proliferation and fibrosis of retrobulbar adipose tissue in TAO patients might be related to the increased expression of collagen (types I, III, and V) and HSP47 and decreased degradation of extracellular matrix.

Keyphrases

adipose tissue
extracellular matrix
poor prognosis
heat shock protein
end stage renal disease
ejection fraction
newly diagnosed
high fat diet
heat shock
heat stress
signaling pathway
type diabetes
prognostic factors
binding protein
long non coding rna
tissue engineering