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KW-2449 and VPA exert therapeutic effects on human neurons and cerebral organoids derived from MECP2-null hESCs.

Ya-Jie XuPei-Pei LiuZhong-Ze YanTing-Wei MiYing-Ying WangQian LiZhao-Qian TengChang-Mei Liu
Published in: Stem cell research & therapy (2022)
These findings suggest that KW-2449 and VPA might be promising drugs for RTT treatment.
Keyphrases
  • induced pluripotent stem cells
  • endothelial cells
  • spinal cord
  • subarachnoid hemorrhage
  • pluripotent stem cells
  • combination therapy
  • brain injury
  • spinal cord injury
  • cerebral ischemia