Role of delay and antibiotics on PERForation rate while waiting appendicECTomy (PERFECT): a protocol for a randomized non-inferiority trial.

K JalavaV SallinenH LampelaH MalmiA LeppäniemiPanu Juhani Mentula

Published in: BJS open (2021)

There are no previous randomized controlled studies for either in-hospital delay or preoperative antibiotic treatment. The trial will yield new level 1 evidence.EU Clinical Trials Register, EudraCT Number: 2019-002348-26; registration number: NCT04378868 (http://www.clinicaltrials.gov).

Keyphrases

phase iii
clinical trial
phase ii
open label
double blind
study protocol
placebo controlled
randomized controlled trial
healthcare
patients undergoing
emergency department
adverse drug
combination therapy
drug induced