Adult heart procurement following circulatory determined death from a donor on venous-venous extracorporeal membrane oxygenation: A case report.
Eyal R NachumJohn HoganMohamed OsmanSimon MesserJennifer BaxterFrancisco OlanoMarius BermanStephen LargePublished in: Perfusion (2021)
Donation after circulatory death in the context of heart transplants is attracting interest and becoming popular in clinical practice. Activity is growing in the United Kingdom, Australia, and the United States. We believe that a prolonged warm ischemic time (time from asystole to reperfusion of the heart on an ex vivo perfusion system) is a primary indicator of adverse outcomes. However, 1.5 liters of blood must be retrieved from the right atrium following sternotomy prolonging warm ischemic time. The patient in the following case report was supported by veno-venous extra-corporeal membrane oxygenation following drowning, further complicated by aspiration-related lung failure. Following circulatory death and a mandatory five-minute stand-off period, 1.5 liters of blood was drained from the circuit as sternotomy began. Surgeons then proceeded to direct procurement of the heart, aiming for least functional warm ischemic time. Following standard implantation, the patient's postoperative recovery has been unremarkable to date.
Keyphrases
- extracorporeal membrane oxygenation
- case report
- acute respiratory distress syndrome
- heart failure
- cerebral ischemia
- respiratory failure
- atrial fibrillation
- clinical practice
- ischemia reperfusion injury
- aortic valve replacement
- patients undergoing
- coronary artery
- mechanical ventilation
- subarachnoid hemorrhage
- pulmonary artery
- blood brain barrier
- left ventricular
- quality improvement
- young adults
- cross sectional
- magnetic resonance imaging
- vena cava
- pulmonary arterial hypertension
- childhood cancer
- acute coronary syndrome
- percutaneous coronary intervention
- catheter ablation