Optimizing expression quantitative trait locus mapping workflows for single-cell studies.

Anna S E CuomoGiordano AlvariChristina B Azodinull nullDavis J McCarthyMarc Jan Bonder

Published in: Genome biology (2021)

We provide recommendations for future single-cell eQTL studies that can yield up to twice as many eQTL discoveries as default approaches ported from bulk studies.

Keyphrases

single cell
case control
rna seq
high resolution
poor prognosis
gene expression
clinical practice
high density