PAX6, brain structure and function in human adults: advanced MRI in aniridia.

Mahinda YogarajahMar MatarinChristian VollmarPamela J ThompsonJohn S DuncanMark SymmsAnthony T MooreJoan LiuMaria ThomVeronica Van HeyningenSanjay M Sisodiya

Published in: Annals of clinical and translational neurology (2016)

These findings suggest a role for PAX6 in the maintenance and consequent functioning of the adult brain, homologous to that found in other tissues. This has significant implications for the understanding and treatment of neurodegenerative diseases.

Keyphrases

resting state
white matter
endothelial cells
magnetic resonance imaging
functional connectivity
dna damage
gene expression
cerebral ischemia
computed tomography
oxidative stress
pluripotent stem cells
multiple sclerosis
magnetic resonance
combination therapy
brain injury
replacement therapy