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The relationship between lipoprotein A and other lipids with prostate cancer risk: A multivariable Mendelian randomisation study.

Anna IoannidouEleanor L WattsAurora Perez-CornagoElizabeth A PlatzIan G MillsTimothy J KeyRuth C Travisnull nullKonstantinos K TsilidisVerena Zuber
Published in: PLoS medicine (2022)
We observed that genetically predicted Lp(a) concentrations were associated with an increased PCa risk. Future studies are required to understand the underlying biological pathways of this finding, as it may inform PCa prevention through Lp(a)-lowering strategies.
Keyphrases
  • prostate cancer
  • radical prostatectomy
  • fatty acid
  • case control
  • low density lipoprotein