Human airway epithelial extracellular vesicle miRNA signature is altered upon asthma development.

Sabine BartelStefania La GruttaGiovanna CilluffoGiovanni PercontiAntonella BongiovanniAgata GiallongoJochen BehrendsJochen KruppaStefanie HermannDapi ChiangMichael W Pfaffl Susanne Krauss-Etschmann

Published in: Allergy (2019)

Our data indicate that secretion of miRNAs in EVs from the airway epithelium, in particular miR-34a, miR-92b, and miR-210, might be involved in the early development of a Th2 response in the airways and asthma.

Keyphrases

cell proliferation
long non coding rna
chronic obstructive pulmonary disease
lung function
long noncoding rna
endothelial cells
cystic fibrosis
allergic rhinitis
electronic health record
machine learning
big data
air pollution
pluripotent stem cells