Pathological complete response as a surrogate to improved survival in human epidermal growth factor receptor-2-positive breast cancer: systematic review and meta-analysis.
Matthew G DaveyFerdia BrowneNicola MillerAoife J LoweryMichael J KerinPublished in: BJS open (2022)
This study confirms pCR as an informative surrogate biomarker for enhanced survival and suggests that it may be used as an appropriate endpoint for clinical research.