Pain intensity, physical function, and depressive symptoms associated with discontinuing long-term opioid therapy in older adults with Alzheimer's disease and related dementias.
Yu-Jung Jenny WeiAlmut G WintersteinSiegfried SchmidtRoger B FillingimMichael J DanielsLaurence SolbergSteven T DeKoskyPublished in: Alzheimer's & dementia : the journal of the Alzheimer's Association (2023)
Discontinuing long-term opioid therapy (LTOT) was associated with lower short- and long-term worsening pain. Discontinuing LTOT was related to lower short- and long-term worsening depression. Discontinuing LTOT was not associated with short- and long-term physical function.