Impact of periodontitis on circulating cell-free DNA levels as a measure of cardiovascular disease.
Gaetano IsolaAlessandro PolizziMarco MascittiSimona SantonocitoVincenzo RonsivalleMarco CicciùPaolo PescePublished in: Clinical oral investigations (2023)
Unbalanced circulating cfDNA concentrations have been indicated to represent a possible risk of CVD and endothelial dysfunction. Periodontitis and periodontitis + CVD patients showed higher circulating cfDNA expression; moreover, the extent of periodontitis significantly predicted higher circulating cfDNA concentrations, suggesting the potential increased risk of developing CVD in periodontitis patients.