Cholinergic deficits and galaninergic hyperinnervation of the nucleus basalis of Meynert in Alzheimer's disease and Lewy body disorders.

Athanasios S AlexandrisL WalkerA K L LiuK E McAleeseM JohnsonR K B PearceSteve M GentlemanJ Attems

Published in: Neuropathology and applied neurobiology (2019)

Our results suggest that galanin upregulation represents an intrinsic response early in Lewy body diseases but which fails with increasing burdens of AD related pathology.

Keyphrases

parkinson disease
traumatic brain injury
poor prognosis
cell proliferation
signaling pathway
deep brain stimulation
mild cognitive impairment