In Silico and In Vitro Studies of the Inhibitory Effect of Antihistamine Drug Cyproheptadine Hydrochloride on Human Salivary Alpha Amylase.

Benguechoua MadjdaBenarous KhedidjaNia SamiraYousfi Mohamed

Published in: Anti-inflammatory & anti-allergy agents in medicinal chemistry (2022)

We conclude that Cyproheptadine hydrochloride, which was studied by docking experiments, exhibited the best inhibitory activity on salivary α-amylase in vitro & in silico.

Keyphrases

molecular docking
endothelial cells
molecular dynamics simulations
molecular dynamics
induced pluripotent stem cells
pluripotent stem cells
protein protein
emergency department
adverse drug
small molecule
drug induced