Transcriptional analysis of multiple ovarian cancer cohorts reveals prognostic and immunomodulatory consequences of ERV expression.

Marina Natoli John GallonHaonan LuAla AmgheibDavid James PinatoFrancesco A MauriTeresa MarafiotiAyse U AkarcaInes UllmoJacey IpEric O AboagyeRobert BrownAnastasios KaradimitrisSadaf Ghaem-Maghami

Published in: Journal for immunotherapy of cancer (2021)

These findings uncover the potential for baseline ERV expression to robustly inform EOC patient prognosis, influence tumor immune infiltration and affect antitumor immunity.

Keyphrases

poor prognosis
gene expression
case report
binding protein
transcription factor
oxidative stress