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Placental lesions and differential expression of pro-and anti-angiogenic growth mediators and oxidative DNA damage marker in placentae of Ghanaian suboptimal and optimal health status pregnant women who later developed preeclampsia.

Enoch Odame AntoDavid Antony CoallEmmanuel Akomanin AsiamahOsei-Owusu AfriyieOtchere Addai-MensahYaw Amo WiafeWkba OwireduChristian ObirikorangMax Efui Annani-AkollorNicholas Akinwale TitiloyeEric AduaEmmanuel AcheampongEvans Asamoah AduStephen OpokuAgartha Odame AntoAugustine TawiahYouxin WangWei Wang
Published in: PloS one (2022)
Increased lesions, oxidative DNA damage, and imbalanced expression between pro-and anti-AGMs are associated more with SHS-embodied PE placentae rather than OHS-embodied PE subtypes, thus potentially allowing differential evaluation of PE.
Keyphrases
  • dna damage
  • pregnant women
  • dna repair
  • oxidative stress
  • anti inflammatory
  • poor prognosis
  • early onset
  • long non coding rna