Placental lesions and differential expression of pro-and anti-angiogenic growth mediators and oxidative DNA damage marker in placentae of Ghanaian suboptimal and optimal health status pregnant women who later developed preeclampsia.
Enoch Odame AntoDavid Antony CoallEmmanuel Akomanin AsiamahOsei-Owusu AfriyieOtchere Addai-MensahYaw Amo WiafeWkba OwireduChristian ObirikorangMax Efui Annani-AkollorNicholas Akinwale TitiloyeEric AduaEmmanuel AcheampongEvans Asamoah AduStephen OpokuAgartha Odame AntoAugustine TawiahYouxin WangWei WangPublished in: PloS one (2022)
Increased lesions, oxidative DNA damage, and imbalanced expression between pro-and anti-AGMs are associated more with SHS-embodied PE placentae rather than OHS-embodied PE subtypes, thus potentially allowing differential evaluation of PE.