Bright ferritin for long-term MR imaging of human embryonic stem cells.
Keyu ZhuangRocco RomagnuoloTamilla Sadikov ValdmanKyle D W VollettDaniel A SzulcHai-Ying Mary ChengMichael A LaflammeHai-Ling Margaret ChengPublished in: Stem cell research & therapy (2023)
The bright-ferritin platform provides the first demonstration of longitudinal cell tracking with signal recall, opening a window on the massive cell death that hESCs undergo in the weeks following transplantation before the surviving cell fraction proliferates to form teratomas.