Handling oxygenation targets in ICU patients with COVID-19-Protocol and statistical analysis plan in the HOT-COVID trial.
Frederik Mølgaard NielsenThomas Lass KlitgaardElena CrescioliSøren Rosborg AagaardAnne Sofie AndreasenLone Musaeus PoulsenMartin SiegemundAnne Craveiro BrøchnerMorten H BestleSusanne Andi IversenBjörn A BrandJon Henrik LaakeThorbjørn GrøfteThomas HildebrandtTheis LangeAnders PernerOlav Lilleholt SchjørringBodil Steen RasmussenPublished in: Acta anaesthesiologica Scandinavica (2021)
The HOT-COVID trial will provide patient-important data on the effect of two oxygenation targets in ICU patients with COVID-19 and hypoxia. This protocol paper describes the background, design and statistical analysis plan for the trial.