Optogenetically controlled human functional motor endplate for testing botulinum neurotoxins.

Juliette Duchesne de LamotteJérôme PolentesFlorine RoussangeLéa LesueurPauline FeurgardAnselme PerrierCamille NicoleauCécile Martinat

Published in: Stem cell research & therapy (2021)

Altogether, our findings demonstrate the promise of optogenetically hiPSC-derived controlled muscle-nerve system for pharmaceutical BoNTs testing and development.

Keyphrases

endothelial cells
skeletal muscle
induced pluripotent stem cells
big data
pluripotent stem cells
machine learning
artificial intelligence
deep learning