Electrocardiographic and genetic characteristics in first degree relatives of hypertrophic cardiomyopathy probands: A descriptive cross-sectional study from Vietnam.
Phong Dinh PhanViet Tuan TranMinh Nhat PhamAnh Trung MaiDat Tuan AnHung Manh PhamPublished in: JRSM cardiovascular disease (2024)
Our results suggested that sarcomere mutations have early consequences on myocardial biology. These findings suggest the possibility of implementing a mutation carrier detection model within families affected by HCM, where ECG could play a central role when combined with other relevant clinical factors. Longitudinal studies on a cohort of G+/LVH- patients are required.
Keyphrases
- hypertrophic cardiomyopathy
- left ventricular
- end stage renal disease
- ejection fraction
- cross sectional
- chronic kidney disease
- newly diagnosed
- heart failure
- prognostic factors
- left atrial
- heart rate variability
- blood pressure
- genome wide
- quality improvement
- mitral valve
- patient reported outcomes
- case control
- copy number
- loop mediated isothermal amplification
- quantum dots