Topical sirolimus 0.1% for treating cutaneous microcystic lymphatic malformations in children and adults (TOPICAL): protocol for a multicenter phase 2, within-person, randomized, double-blind, vehicle-controlled clinical trial.

Sophie LeducqAgnès CailleSébastien BarbarotNathalie BénétonDidier BessisOlivia BoccaraAnne-Claire BursztejnChristine ChiaveriniAnne DompmartinCatherine DroitcourtValérie GissotDominique GogaLaurent GuibaudDenis HerbreteauAnne Le TouzeChristine Léauté-LabrèzeGérard LoretteStéphanie MalletLudovic MartinJuliette Mazereeuw-HautierAlice PhanPatrice PlantinIsabelle QuéréPierre VabresHélène BourgoinBruno GiraudeauAnnabel Maruaninull null

Published in: Trials (2019)

ClinicalTrials.gov, NCT03972592. Registered on 3 June 2019. EU Clinical Trials Register EudraCT, 2018-001359-11.

Keyphrases

double blind
clinical trial
placebo controlled
phase ii
phase iii
open label
wound healing
study protocol
young adults
randomized controlled trial
lymph node