HDGFL2 cryptic proteins report presence of TDP-43 pathology in neurodegenerative diseases.
Anna CalliariLillian M DaughrityEllen A AlbagliPaula Castellanos OteroMei YueKaren Jansen-WestNaeyma N IslamThomas CaulfieldBailey RawlinsonMichael DeTureCasey CookNeill R Graff-RadfordGregory S DayBradley F BoeveDavid S KnopmanRonald C PetersenKeith A JosephsBjörn OskarssonAaron D GitlerDennis W DicksonTania F GendronMercedes PrudencioMichael E WardYong-Jie ZhangLeonard PetrucelliPublished in: Molecular neurodegeneration (2024)
This letter demonstrates the potential of novel cryptic proteins resulting from TAR DNA-binding protein 43 (TDP-43) dysfunction as markers of TDP-43 pathology in neurodegenerative diseases.