Leonard Petrucelli

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 43

Top Topics

Coronavirus Disease

Amyotrophic Lateral Sclerosis

Lipopolysaccharide Induced

Top Venues

Science translational medicine

Molecular neurodegeneration

Journal of neurology

Science (New York, N.Y.)

This page only lists publications with an associated author ORCID identifier.

Publications

Anna Calliari, Lillian M Daughrity, Ellen A Albagli, Paula Castellanos Otero, Mei Yue, Karen Jansen-West, Naeyma N Islam, Thomas Caulfield, Bailey Rawlinson, Michael DeTure, Casey Cook, Neill R Graff-Radford, Gregory S Day, Bradley F Boeve, David S Knopman, Ronald C Petersen, Keith A Josephs, Björn Oskarsson, Aaron D Gitler, Dennis W Dickson, Tania F Gendron, Mercedes Prudencio, Michael E Ward, Yong-Jie Zhang, Leonard Petrucelli
HDGFL2 cryptic proteins report presence of TDP-43 pathology in neurodegenerative diseases. Molecular neurodegeneration 19 (1) (2024)
Jordan D Marks, Virginia Estades Ayuso, Yari Carlomagno, Mei Yue, Tiffany W Todd, Ying Hao, Ziyi Li, Zachary T McEachin, Anantharaman Shantaraman, Duc M Duong, Lillian M Daughrity, Karen R Jansen-West, Wei Shao, Anna Calliari, Jesus Gonzalez Bejarano, Michael A DeTure, Bailey Rawlinson, Monica Castanedes Casey, Meredith T Lilley, Megan H Donahue, Vidhya Maheswari Jawahar, Bradley F Boeve, Ronald C Petersen, David S Knopman, Björn E Oskarsson, Neill R Graff-Radford, Zbigniew K Wszolek, Gourisankar Ghosh, Keith Anthony Josephs, Yue A Qi, Nicholas T Seyfried, Michael Emmerson Ward, Yong-Jie Zhang, Mercedes Prudencio, Leonard Petrucelli, Casey N Cook
TMEM106B core deposition associates with TDP-43 pathology and is increased in risk SNP carriers for frontotemporal dementia. Science translational medicine 16 (730) (2024)
Sahba Seddighi, Yue A Qi, Anna-Leigh Brown, Oscar G Wilkins, Colleen C Bereda, Cedric Belair, Yong-Jie Zhang, Mercedes Prudencio, Matthew J Keuss, Aditya Khandeshi, Sarah R Pickles, Sarah E Kargbo-Hill, James Hawrot, Daniel M Ramos, Hebao Yuan, Jessica Roberts, Erika Kelmer Sacramento, Syed I Shah, Mike A Nalls, Jennifer M Colón-Mercado, Joel F Reyes, Veronica H Ryan, Matthew P Nelson, Casey N Cook, Ziyi Li, Laurel A Screven, Justin Y Kwan, Puja R Mehta, Matteo Zanovello, Martina Hallegger, Anantharaman Shantaraman, Lingyan Ping, Yuka Koike, Björn E Oskarsson, Nathan P Staff, Duc M Duong, Aisha Ahmed, Maria Secrier, Jernej Ule, Steven Jacobson, Daniel S Reich, Jonathan Daniel Rohrer, Andrea Malaspina, Gourisankar Ghosh, Jonathan D Glass, Alessandro Ori, Nicholas T Seyfried, Manolis Maragkakis, Leonard Petrucelli, Pietro Fratta, Michael Emmerson Ward
Mis-spliced transcripts generate de novo proteins in TDP-43-related ALS/FTD. Science translational medicine 16 (734) (2024)
Sahba Seddighi, Yue A Qi, Anna-Leigh Brown, Oscar G Wilkins, Colleen C Bereda, Cedric Belair, Yong-Jie Zhang, Mercedes Prudencio, Matthew J Keuss, Aditya Khandeshi, Sarah R Pickles, Sarah E Kargbo-Hill, James Hawrot, Daniel M Ramos, Hebao Yuan, Jessica Roberts, Erika Kelmer Sacramento, Syed I Shah, Mike A Nalls, Jennifer M Colón-Mercado, Joel F Reyes, Veronica H Ryan, Matthew P Nelson, Casey N Cook, Ziyi Li, Laurel A Screven, Justin Y Kwan, Puja R Mehta, Matteo Zanovello, Martina Hallegger, Anantharaman Shantaraman, Lingyan Ping, Yuka Koike, Björn E Oskarsson, Nathan P Staff, Duc M Duong, Aisha Ahmed, Maria Secrier, Jernej Ule, Steven Jacobson, Daniel S Reich, Jonathan Daniel Rohrer, Andrea Malaspina, Gourisankar Ghosh, Jonathan D Glass, Alessandro Ori, Nicholas T Seyfried, Manolis Maragkakis, Leonard Petrucelli, Pietro Fratta, Michael Emmerson Ward
Mis-spliced transcripts generate de novo proteins in TDP-43-related ALS/FTD. Science translational medicine 16 (734) (2024)
Anna Calliari, Lillian M Daughrity, Ellen A Albagli, Paula Castellanos Otero, Mei Yue, Karen Jansen-West, Naeyma N Islam, Thomas Caulfield, Bailey Rawlinson, Michael DeTure, Casey Cook, Neill R Graff-Radford, Gregory S Day, Bradley F Boeve, David S Knopman, Ronald C Petersen, Keith A Josephs, Björn Oskarsson, Aaron D Gitler, Dennis W Dickson, Tania F Gendron, Mercedes Prudencio, Michael E Ward, Yong-Jie Zhang, Leonard Petrucelli
Correction: HDGFL2 cryptic proteins report presence of TDP-43 pathology in neurodegenerative diseases. Molecular neurodegeneration 19 (1) (2024)
Jordan D Marks, Virginia Estades Ayuso, Yari Carlomagno, Mei Yue, Tiffany W Todd, Ying Hao, Ziyi Li, Zachary T McEachin, Anantharaman Shantaraman, Duc M Duong, Lillian M Daughrity, Karen R Jansen-West, Wei Shao, Anna Calliari, Jesus Gonzalez Bejarano, Michael A DeTure, Bailey Rawlinson, Monica Castanedes Casey, Meredith T Lilley, Megan H Donahue, Vidhya Maheswari Jawahar, Bradley F Boeve, Ronald C Petersen, David S Knopman, Björn E Oskarsson, Neill R Graff-Radford, Zbigniew K Wszolek, Gourisankar Ghosh, Keith Anthony Josephs, Yue A Qi, Nicholas T Seyfried, Michael Emmerson Ward, Yong-Jie Zhang, Mercedes Prudencio, Leonard Petrucelli, Casey N Cook
TMEM106B core deposition associates with TDP-43 pathology and is increased in risk SNP carriers for frontotemporal dementia. Science translational medicine 16 (730) (2024)
Sahba Seddighi, Yue A Qi, Anna-Leigh Brown, Oscar G Wilkins, Colleen C Bereda, Cedric Belair, Yong-Jie Zhang, Mercedes Prudencio, Matthew J Keuss, Aditya Khandeshi, Sarah R Pickles, Sarah E Kargbo-Hill, James Hawrot, Daniel M Ramos, Hebao Yuan, Jessica Roberts, Erika Kelmer Sacramento, Syed I Shah, Mike A Nalls, Jennifer M Colón-Mercado, Joel F Reyes, Veronica H Ryan, Matthew P Nelson, Casey N Cook, Ziyi Li, Laurel A Screven, Justin Y Kwan, Puja R Mehta, Matteo Zanovello, Martina Hallegger, Anantharaman Shantaraman, Lingyan Ping, Yuka Koike, Björn E Oskarsson, Nathan P Staff, Duc M Duong, Aisha Ahmed, Maria Secrier, Jernej Ule, Steven Jacobson, Daniel S Reich, Jonathan Daniel Rohrer, Andrea Malaspina, Gourisankar Ghosh, Jonathan D Glass, Alessandro Ori, Nicholas T Seyfried, Manolis Maragkakis, Leonard Petrucelli, Pietro Fratta, Michael Emmerson Ward
Mis-spliced transcripts generate de novo proteins in TDP-43-related ALS/FTD. Science translational medicine 16 (734) (2024)
Sahba Seddighi, Yue A Qi, Anna-Leigh Brown, Oscar G Wilkins, Colleen C Bereda, Cedric Belair, Yong-Jie Zhang, Mercedes Prudencio, Matthew J Keuss, Aditya Khandeshi, Sarah R Pickles, Sarah E Kargbo-Hill, James Hawrot, Daniel M Ramos, Hebao Yuan, Jessica Roberts, Erika Kelmer Sacramento, Syed I Shah, Mike A Nalls, Jennifer M Colón-Mercado, Joel F Reyes, Veronica H Ryan, Matthew P Nelson, Casey N Cook, Ziyi Li, Laurel A Screven, Justin Y Kwan, Puja R Mehta, Matteo Zanovello, Martina Hallegger, Anantharaman Shantaraman, Lingyan Ping, Yuka Koike, Björn E Oskarsson, Nathan P Staff, Duc M Duong, Aisha Ahmed, Maria Secrier, Jernej Ule, Steven Jacobson, Daniel S Reich, Jonathan Daniel Rohrer, Andrea Malaspina, Gourisankar Ghosh, Jonathan D Glass, Alessandro Ori, Nicholas T Seyfried, Manolis Maragkakis, Leonard Petrucelli, Pietro Fratta, Michael Emmerson Ward
Mis-spliced transcripts generate de novo proteins in TDP-43-related ALS/FTD. Science translational medicine (2024)
Sahba Seddighi, Yue A Qi, Anna-Leigh Brown, Oscar G Wilkins, Colleen C Bereda, Cedric Belair, Yong-Jie Zhang, Mercedes Prudencio, Matthew J Keuss, Aditya Khandeshi, Sarah R Pickles, Sarah E Kargbo-Hill, James Hawrot, Daniel M Ramos, Hebao Yuan, Jessica Roberts, Erika Kelmer Sacramento, Syed I Shah, Mike A Nalls, Jennifer M Colón-Mercado, Joel F Reyes, Veronica H Ryan, Matthew P Nelson, Casey N Cook, Ziyi Li, Laurel A Screven, Justin Y Kwan, Puja R Mehta, Matteo Zanovello, Martina Hallegger, Anantharaman Shantaraman, Lingyan Ping, Yuka Koike, Björn E Oskarsson, Nathan P Staff, Duc M Duong, Aisha Ahmed, Maria Secrier, Jernej Ule, Steven Jacobson, Daniel S Reich, Jonathan Daniel Rohrer, Andrea Malaspina, Gourisankar Ghosh, Jonathan D Glass, Alessandro Ori, Nicholas T Seyfried, Manolis Maragkakis, Leonard Petrucelli, Pietro Fratta, Michael Emmerson Ward
Mis-spliced transcripts generate de novo proteins in TDP-43-related ALS/FTD. Science translational medicine 16 (734) (2024)
Anna Calliari, Lillian M Daughrity, Ellen A Albagli, Paula Castellanos Otero, Mei Yue, Karen Jansen-West, Naeyma N Islam, Thomas Caulfield, Bailey Rawlinson, Michael DeTure, Casey Cook, Neill R Graff-Radford, Gregory S Day, Bradley F Boeve, David S Knopman, Ronald C Petersen, Keith A Josephs, Björn Oskarsson, Aaron D Gitler, Dennis W Dickson, Tania F Gendron, Mercedes Prudencio, Michael E Ward, Yong-Jie Zhang, Leonard Petrucelli
Correction: HDGFL2 cryptic proteins report presence of TDP-43 pathology in neurodegenerative diseases. Molecular neurodegeneration 19 (1) (2024)
Sahba Seddighi, Yue A Qi, Anna-Leigh Brown, Oscar G Wilkins, Colleen C Bereda, Cedric Belair, Yong-Jie Zhang, Mercedes Prudencio, Matthew J Keuss, Aditya Khandeshi, Sarah R Pickles, Sarah E Kargbo-Hill, James Hawrot, Daniel M Ramos, Hebao Yuan, Jessica Roberts, Erika Kelmer Sacramento, Syed I Shah, Mike A Nalls, Jennifer M Colón-Mercado, Joel F Reyes, Veronica H Ryan, Matthew P Nelson, Casey N Cook, Ziyi Li, Laurel A Screven, Justin Y Kwan, Puja R Mehta, Matteo Zanovello, Martina Hallegger, Anantharaman Shantaraman, Lingyan Ping, Yuka Koike, Björn E Oskarsson, Nathan P Staff, Duc M Duong, Aisha Ahmed, Maria Secrier, Jernej Ule, Steven Jacobson, Daniel S Reich, Jonathan Daniel Rohrer, Andrea Malaspina, Gourisankar Ghosh, Jonathan D Glass, Alessandro Ori, Nicholas T Seyfried, Manolis Maragkakis, Leonard Petrucelli, Pietro Fratta, Michael Emmerson Ward
Mis-spliced transcripts generate de novo proteins in TDP-43-related ALS/FTD. Science translational medicine (2024)
Sahba Seddighi, Yue A Qi, Anna-Leigh Brown, Oscar G Wilkins, Colleen C Bereda, Cedric Belair, Yong-Jie Zhang, Mercedes Prudencio, Matthew J Keuss, Aditya Khandeshi, Sarah R Pickles, Sarah E Kargbo-Hill, James Hawrot, Daniel M Ramos, Hebao Yuan, Jessica Roberts, Erika Kelmer Sacramento, Syed I Shah, Mike A Nalls, Jennifer M Colón-Mercado, Joel F Reyes, Veronica H Ryan, Matthew P Nelson, Casey N Cook, Ziyi Li, Laurel A Screven, Justin Y Kwan, Puja R Mehta, Matteo Zanovello, Martina Hallegger, Anantharaman Shantaraman, Lingyan Ping, Yuka Koike, Björn E Oskarsson, Nathan P Staff, Duc M Duong, Aisha Ahmed, Maria Secrier, Jernej Ule, Steven Jacobson, Daniel S Reich, Jonathan Daniel Rohrer, Andrea Malaspina, Gourisankar Ghosh, Jonathan D Glass, Alessandro Ori, Nicholas T Seyfried, Manolis Maragkakis, Leonard Petrucelli, Pietro Fratta, Michael Emmerson Ward
Mis-spliced transcripts generate de novo proteins in TDP-43-related ALS/FTD. Science translational medicine 16 (734) (2024)
Sahba Seddighi, Yue A Qi, Anna-Leigh Brown, Oscar G Wilkins, Colleen C Bereda, Cedric Belair, Yong-Jie Zhang, Mercedes Prudencio, Matthew J Keuss, Aditya Khandeshi, Sarah R Pickles, Sarah E Kargbo-Hill, James Hawrot, Daniel M Ramos, Hebao Yuan, Jessica Roberts, Erika Kelmer Sacramento, Syed I Shah, Mike A Nalls, Jennifer M Colón-Mercado, Joel F Reyes, Veronica H Ryan, Matthew P Nelson, Casey N Cook, Ziyi Li, Laurel A Screven, Justin Y Kwan, Puja R Mehta, Matteo Zanovello, Martina Hallegger, Anantharaman Shantaraman, Lingyan Ping, Yuka Koike, Björn E Oskarsson, Nathan P Staff, Duc M Duong, Aisha Ahmed, Maria Secrier, Jernej Ule, Steven Jacobson, Daniel S Reich, Jonathan Daniel Rohrer, Andrea Malaspina, Gourisankar Ghosh, Jonathan D Glass, Alessandro Ori, Nicholas T Seyfried, Manolis Maragkakis, Leonard Petrucelli, Pietro Fratta, Michael Emmerson Ward
Mis-spliced transcripts generate de novo proteins in TDP-43-related ALS/FTD. Science translational medicine 16 (734) (2024)
Anna Calliari, Lillian M Daughrity, Ellen A Albagli, Paula Castellanos Otero, Mei Yue, Karen Jansen-West, Naeyma N Islam, Thomas Caulfield, Bailey Rawlinson, Michael DeTure, Casey Cook, Neill R Graff-Radford, Gregory S Day, Bradley F Boeve, David S Knopman, Ronald C Petersen, Keith A Josephs, Björn Oskarsson, Aaron D Gitler, Dennis W Dickson, Tania F Gendron, Mercedes Prudencio, Michael E Ward, Yong-Jie Zhang, Leonard Petrucelli
HDGFL2 cryptic proteins report presence of TDP-43 pathology in neurodegenerative diseases. Molecular neurodegeneration 19 (1) (2024)
Jordan D Marks, Virginia Estades Ayuso, Yari Carlomagno, Mei Yue, Tiffany W Todd, Ying Hao, Ziyi Li, Zachary T McEachin, Anantharaman Shantaraman, Duc M Duong, Lillian M Daughrity, Karen R Jansen-West, Wei Shao, Anna Calliari, Jesus Gonzalez Bejarano, Michael A DeTure, Bailey Rawlinson, Monica Castanedes Casey, Meredith T Lilley, Megan H Donahue, Vidhya Maheswari Jawahar, Bradley F Boeve, Ronald C Petersen, David S Knopman, Björn E Oskarsson, Neill R Graff-Radford, Zbigniew K Wszolek, Gourisankar Ghosh, Keith Anthony Josephs, Yue A Qi, Nicholas T Seyfried, Michael Emmerson Ward, Yong-Jie Zhang, Mercedes Prudencio, Leonard Petrucelli, Casey N Cook
TMEM106B core deposition associates with TDP-43 pathology and is increased in risk SNP carriers for frontotemporal dementia. Science translational medicine 16 (730) (2024)
Sahba Seddighi, Yue A Qi, Anna-Leigh Brown, Oscar G Wilkins, Colleen C Bereda, Cedric Belair, Yong-Jie Zhang, Mercedes Prudencio, Matthew J Keuss, Aditya Khandeshi, Sarah R Pickles, Sarah E Kargbo-Hill, James Hawrot, Daniel M Ramos, Hebao Yuan, Jessica Roberts, Erika Kelmer Sacramento, Syed I Shah, Mike A Nalls, Jennifer M Colón-Mercado, Joel F Reyes, Veronica H Ryan, Matthew P Nelson, Casey N Cook, Ziyi Li, Laurel A Screven, Justin Y Kwan, Puja R Mehta, Matteo Zanovello, Martina Hallegger, Anantharaman Shantaraman, Lingyan Ping, Yuka Koike, Björn E Oskarsson, Nathan P Staff, Duc M Duong, Aisha Ahmed, Maria Secrier, Jernej Ule, Steven Jacobson, Daniel S Reich, Jonathan Daniel Rohrer, Andrea Malaspina, Gourisankar Ghosh, Jonathan D Glass, Alessandro Ori, Nicholas T Seyfried, Manolis Maragkakis, Leonard Petrucelli, Pietro Fratta, Michael Emmerson Ward
Mis-spliced transcripts generate de novo proteins in TDP-43-related ALS/FTD. Science translational medicine 16 (734) (2024)
Jordan D Marks, Virginia Estades Ayuso, Yari Carlomagno, Mei Yue, Tiffany W Todd, Ying Hao, Ziyi Li, Zachary T McEachin, Anantharaman Shantaraman, Duc M Duong, Lillian M Daughrity, Karen R Jansen-West, Wei Shao, Anna Calliari, Jesus Gonzalez Bejarano, Michael A DeTure, Bailey Rawlinson, Monica Castanedes Casey, Meredith T Lilley, Megan H Donahue, Vidhya Maheswari Jawahar, Bradley F Boeve, Ronald C Petersen, David S Knopman, Björn E Oskarsson, Neill R Graff-Radford, Zbigniew K Wszolek, Gourisankar Ghosh, Keith Anthony Josephs, Yue A Qi, Nicholas T Seyfried, Michael Emmerson Ward, Yong-Jie Zhang, Mercedes Prudencio, Leonard Petrucelli, Casey N Cook
TMEM106B core deposition associates with TDP-43 pathology and is increased in risk SNP carriers for frontotemporal dementia. Science translational medicine 16 (730) (2024)
Anna Calliari, Lillian M Daughrity, Ellen A Albagli, Paula Castellanos Otero, Mei Yue, Karen Jansen-West, Naeyma N Islam, Thomas Caulfield, Bailey Rawlinson, Michael DeTure, Casey Cook, Neill R Graff-Radford, Gregory S Day, Bradley F Boeve, David S Knopman, Ronald C Petersen, Keith A Josephs, Björn Oskarsson, Aaron D Gitler, Dennis W Dickson, Tania F Gendron, Mercedes Prudencio, Michael E Ward, Yong-Jie Zhang, Leonard Petrucelli
HDGFL2 cryptic proteins report presence of TDP-43 pathology in neurodegenerative diseases. Molecular neurodegeneration 19 (1) (2024)
Jordan D Marks, Virginia Estades Ayuso, Yari Carlomagno, Mei Yue, Tiffany W Todd, Ying Hao, Ziyi Li, Zachary T McEachin, Anantharaman Shantaraman, Duc M Duong, Lillian M Daughrity, Karen R Jansen-West, Wei Shao, Anna Calliari, Jesus Gonzalez Bejarano, Michael A DeTure, Bailey Rawlinson, Monica Castanedes Casey, Meredith T Lilley, Megan H Donahue, Vidhya Maheswari Jawahar, Bradley F Boeve, Ronald C Petersen, David S Knopman, Björn E Oskarsson, Neill R Graff-Radford, Zbigniew K Wszolek, Gourisankar Ghosh, Keith Anthony Josephs, Yue A Qi, Nicholas T Seyfried, Michael Emmerson Ward, Yong-Jie Zhang, Mercedes Prudencio, Leonard Petrucelli, Casey N Cook
TMEM106B core deposition associates with TDP-43 pathology and is increased in risk SNP carriers for frontotemporal dementia. Science translational medicine 16 (730) (2024)
Anna Calliari, Lillian M Daughrity, Ellen A Albagli, Paula Castellanos Otero, Mei Yue, Karen Jansen-West, Naeyma N Islam, Thomas Caulfield, Bailey Rawlinson, Michael DeTure, Casey Cook, Neill R Graff-Radford, Gregory S Day, Bradley F Boeve, David S Knopman, Ronald C Petersen, Keith A Josephs, Björn Oskarsson, Aaron D Gitler, Dennis W Dickson, Tania F Gendron, Mercedes Prudencio, Michael E Ward, Yong-Jie Zhang, Leonard Petrucelli
HDGFL2 cryptic proteins report presence of TDP-43 pathology in neurodegenerative diseases. Molecular neurodegeneration 19 (1) (2024)
Anna Calliari, Lillian M Daughrity, Ellen A Albagli, Paula Castellanos Otero, Mei Yue, Karen Jansen-West, Naeyma N Islam, Thomas Caulfield, Bailey Rawlinson, Michael DeTure, Casey Cook, Neill R Graff-Radford, Gregory S Day, Bradley F Boeve, David S Knopman, Ronald C Petersen, Keith A Josephs, Björn Oskarsson, Aaron D Gitler, Dennis W Dickson, Tania F Gendron, Mercedes Prudencio, Michael E Ward, Yong-Jie Zhang, Leonard Petrucelli
HDGFL2 cryptic proteins report presence of TDP-43 pathology in neurodegenerative diseases. Molecular neurodegeneration 19 (1) (2024)
Jordan D Marks, Virginia Estades Ayuso, Yari Carlomagno, Mei Yue, Tiffany W Todd, Ying Hao, Ziyi Li, Zachary T McEachin, Anantharaman Shantaraman, Duc M Duong, Lillian M Daughrity, Karen R Jansen-West, Wei Shao, Anna Calliari, Jesus Gonzalez Bejarano, Michael A DeTure, Bailey Rawlinson, Monica Castanedes Casey, Meredith T Lilley, Megan H Donahue, Vidhya Maheswari Jawahar, Bradley F Boeve, Ronald C Petersen, David S Knopman, Björn E Oskarsson, Neill R Graff-Radford, Zbigniew K Wszolek, Gourisankar Ghosh, Keith Anthony Josephs, Yue A Qi, Nicholas T Seyfried, Michael Emmerson Ward, Yong-Jie Zhang, Mercedes Prudencio, Leonard Petrucelli, Casey N Cook
TMEM106B core deposition associates with TDP-43 pathology and is increased in risk SNP carriers for frontotemporal dementia. Science translational medicine 16 (730) (2024)
Jordan D Marks, Virginia Estades Ayuso, Yari Carlomagno, Mei Yue, Tiffany W Todd, Ying Hao, Ziyi Li, Zachary T McEachin, Anantharaman Shantaraman, Duc M Duong, Lillian M Daughrity, Karen R Jansen-West, Wei Shao, Anna Calliari, Jesus Gonzalez Bejarano, Michael A DeTure, Bailey Rawlinson, Monica Castanedes Casey, Meredith T Lilley, Megan H Donahue, Vidhya Maheswari Jawahar, Bradley F Boeve, Ronald C Petersen, David S Knopman, Björn E Oskarsson, Neill R Graff-Radford, Zbigniew K Wszolek, Gourisankar Ghosh, Keith Anthony Josephs, Yue A Qi, Nicholas T Seyfried, Michael Emmerson Ward, Yong-Jie Zhang, Mercedes Prudencio, Leonard Petrucelli, Casey N Cook
TMEM106B core deposition associates with TDP-43 pathology and is increased in risk SNP carriers for frontotemporal dementia. Science translational medicine 16 (730) (2024)
Jordan D Marks, Virginia Estades Ayuso, Yari Carlomagno, Mei Yue, Tiffany W Todd, Ying Hao, Ziyi Li, Zachary T McEachin, Anantharaman Shantaraman, Duc M Duong, Lillian M Daughrity, Karen R Jansen-West, Wei Shao, Anna Calliari, Jesus Gonzalez Bejarano, Michael A DeTure, Bailey Rawlinson, Monica Castanedes Casey, Meredith T Lilley, Megan H Donahue, Vidhya Maheswari Jawahar, Bradley F Boeve, Ronald C Petersen, David S Knopman, Björn E Oskarsson, Neill R Graff-Radford, Zbigniew K Wszolek, Gourisankar Ghosh, Keith Anthony Josephs, Yue A Qi, Nicholas T Seyfried, Michael Emmerson Ward, Yong-Jie Zhang, Mercedes Prudencio, Leonard Petrucelli, Casey N Cook
TMEM106B core deposition associates with TDP-43 pathology and is increased in risk SNP carriers for frontotemporal dementia. Science translational medicine 16 (730) (2024)
Jordan D Marks, Virginia Estades Ayuso, Yari Carlomagno, Mei Yue, Tiffany W Todd, Ying Hao, Ziyi Li, Zachary T McEachin, Anantharaman Shantaraman, Duc M Duong, Lillian M Daughrity, Karen R Jansen-West, Wei Shao, Anna Calliari, Jesus Gonzalez Bejarano, Michael A DeTure, Bailey Rawlinson, Monica Castanedes Casey, Meredith T Lilley, Megan H Donahue, Vidhya Maheswari Jawahar, Bradley F Boeve, Ronald C Petersen, David S Knopman, Björn E Oskarsson, Neill R Graff-Radford, Zbigniew K Wszolek, Gourisankar Ghosh, Keith Anthony Josephs, Yue A Qi, Nicholas T Seyfried, Michael Emmerson Ward, Yong-Jie Zhang, Mercedes Prudencio, Leonard Petrucelli, Casey N Cook
TMEM106B core deposition associates with TDP-43 pathology and is increased in risk SNP carriers for frontotemporal dementia. Science translational medicine 16 (730) (2024)
Sahba Seddighi, Yue A Qi, Anna-Leigh Brown, Oscar G Wilkins, Colleen C Bereda, Cedric Belair, Yong-Jie Zhang, Mercedes Prudencio, Matthew J Keuss, Aditya Khandeshi, Sarah R Pickles, Sarah E Kargbo-Hill, James Hawrot, Daniel M Ramos, Hebao Yuan, Jessica Roberts, Erika Kelmer Sacramento, Syed I Shah, Mike A Nalls, Jennifer M Colón-Mercado, Joel F Reyes, Veronica H Ryan, Matthew P Nelson, Casey N Cook, Ziyi Li, Laurel A Screven, Justin Y Kwan, Puja R Mehta, Matteo Zanovello, Martina Hallegger, Anantharaman Shantaraman, Lingyan Ping, Yuka Koike, Björn E Oskarsson, Nathan P Staff, Duc M Duong, Aisha Ahmed, Maria Secrier, Jernej Ule, Steven Jacobson, Daniel S Reich, Jonathan Daniel Rohrer, Andrea Malaspina, Gourisankar Ghosh, Jonathan D Glass, Alessandro Ori, Nicholas T Seyfried, Manolis Maragkakis, Leonard Petrucelli, Pietro Fratta, Michael Emmerson Ward
Mis-spliced transcripts generate de novo proteins in TDP-43-related ALS/FTD. Science translational medicine 16 (734) (2024)
Anna Calliari, Lillian M Daughrity, Ellen A Albagli, Paula Castellanos Otero, Mei Yue, Karen Jansen-West, Naeyma N Islam, Thomas Caulfield, Bailey Rawlinson, Michael DeTure, Casey Cook, Neill R Graff-Radford, Gregory S Day, Bradley F Boeve, David S Knopman, Ronald C Petersen, Keith A Josephs, Björn Oskarsson, Aaron D Gitler, Dennis W Dickson, Tania F Gendron, Mercedes Prudencio, Michael E Ward, Yong-Jie Zhang, Leonard Petrucelli
HDGFL2 cryptic proteins report presence of TDP-43 pathology in neurodegenerative diseases. Molecular neurodegeneration 19 (1) (2024)
Yuka Koike, Sarah Pickles, Virginia Estades Ayuso, Karen Jansen-West, Yue A Qi, Ziyi Li, Lillian M Daughrity, Mei Yue, Yong-Jie Zhang, Casey N Cook, Dennis W Dickson, Michael Ward, Leonard Petrucelli, Mercedes Prudencio
TDP-43 and other hnRNPs regulate cryptic exon inclusion of a key ALS/FTD risk gene, UNC13A. PLoS biology 21 (3) (2023)
Ahmed Abdelhak, Lorenzo Barba, Michele Romoli, Pascal Benkert, Francesco Conversi, Lucio D'Anna, Ruturaj R Masvekar, Bibiana Bielekova, Mercedes Prudencio, Leonard Petrucelli, James F Meschia, Young Erben, Roberto Furlan, Rebecca De Lorenzo, Alessandra Mandelli, Raoul Sutter, Lisa Hert, Varenka Epple, Damiano Marastoni, Johann Sellner, Petra Steinacker, Anne Hege Aamodt, Lars Heggelund, Anne Margarita Dyrhol-Riise, Johan Virhammar, David Fällmar, Elham Rostami, Eva Kumlien, Kaj Blennow, Henrik Zetterberg, Hayrettin Tumani, Simona Sacco, Ari J Green, Markus Otto, Jens Kuhle, Raffaele Ornello, Matteo Foschi, Markus Otto
Prognostic performance of blood neurofilament light chain protein in hospitalized COVID-19 patients without major central nervous system manifestations: an individual participant data meta-analysis. Journal of neurology (2023)
Ahmed Abdelhak, Lorenzo Barba, Michele Romoli, Pascal Benkert, Francesco Conversi, Lucio D'Anna, Ruturaj R Masvekar, Bibiana Bielekova, Mercedes Prudencio, Leonard Petrucelli, James F Meschia, Young Erben, Roberto Furlan, Rebecca De Lorenzo, Alessandra Mandelli, Raoul Sutter, Lisa Hert, Varenka Epple, Damiano Marastoni, Johann Sellner, Petra Steinacker, Anne Hege Aamodt, Lars Heggelund, Anne Margarita Dyrhol-Riise, Johan Virhammar, David Fällmar, Elham Rostami, Eva Kumlien, Kaj Blennow, Henrik Zetterberg, Hayrettin Tumani, Simona Sacco, Ari J Green, Markus Otto, Jens Kuhle, Raffaele Ornello, Matteo Foschi, Markus Otto
Prognostic performance of blood neurofilament light chain protein in hospitalized COVID-19 patients without major central nervous system manifestations: an individual participant data meta-analysis. Journal of neurology (2023)
Tania F Gendron, Leonard Petrucelli
Immunological drivers of amyotrophic lateral sclerosis. Science translational medicine 15 (721) (2023)
Yuka Koike, Sarah Pickles, Virginia Estades Ayuso, Karen Jansen-West, Yue A Qi, Ziyi Li, Lillian M Daughrity, Mei Yue, Yong-Jie Zhang, Casey N Cook, Dennis W Dickson, Michael Ward, Leonard Petrucelli, Mercedes Prudencio
TDP-43 and other hnRNPs regulate cryptic exon inclusion of a key ALS/FTD risk gene, UNC13A. PLoS biology 21 (3) (2023)
Hector Garcia-Moreno, Mercedes Prudencio, Gilbert Thomas-Black, Nita Solanky, Karen R Jansen-West, Rana Hanna Al-Shaikh, Amanda J Heslegrave, Henrik Zetterberg, Magda M Santana, Luis Pereira de Almeida, Ana Vasconcelos-Ferreira, Cristina Januário, Jon Infante, Jennifer Faber, Thomas Klockgether, Kathrin Reetz, Mafalda Raposo, Ana F Ferreira, Manuela Lima, Ludger Schöls, Matthis Synofzik, Jeannette Hübener, Andreas Puschmann, Sorina Gorcenco, Zbigniew K Wszolek, Leonard Petrucelli, Paola Giunti
Tau and neurofilament light-chain as fluid biomarkers in spinocerebellar ataxia type 3. European journal of neurology 29 (8) (2022)
Wei Shao, Tiffany W Todd, Yanwei Wu, Caroline Y Jones, Jimei Tong, Karen R Jansen-West, Lillian M Daughrity, Jinyoung Park, Yuka Koike, Aishe Kurti, Mei Yue, Monica Castanedes Casey, Giulia Del Rosso, Judith A Dunmore, Desiree Zanetti Alepuz, Björn E Oskarsson, Gourisankar Ghosh, Casey N Cook, Mercedes Prudencio, Tania F Gendron, John D Fryer, Yong-Jie Zhang, Leonard Petrucelli
Two FTD-ALS genes converge on the endosomal pathway to induce TDP-43 pathology and degeneration. Science (New York, N.Y.) 378 (6615) (2022)
Junli Gao, Quinlan T Mewborne, Amandeep Girdhar, Udit Sheth, Alyssa N Coyne, Ritika Punathil, Bong Gu Kang, Morgan Dasovich, Austin M Veire, Mariely DeJesus Hernandez, Shuaichen Liu, Zheng Shi, Ruxandra Dafinca, Elise Fouquerel, Kevin Talbot, Tae-In Kam, Yong-Jie Zhang, Gourisankar Ghosh, Leonard Petrucelli, Marka van Blitterswijk, Lin Guo, Ted M Dawson, Valina L Dawson, Anthony K L Leung, Thomas E Lloyd, Tania F Gendron, Jeffrey D Rothstein, Ke Zhang
Poly(ADP-ribose) promotes toxicity of C9ORF72 arginine-rich dipeptide repeat proteins. Science translational medicine 14 (662) (2022)
Tiffany W Todd, Leonard Petrucelli
Modelling amyotrophic lateral sclerosis in rodents. Nature reviews. Neuroscience 23 (4) (2022)
Mercedes Prudencio, Young Erben, Christopher P Marquez, Karen R Jansen-West, Camila Franco-Mesa, Michael G Heckman, Launia J White, Judith A Dunmore, Casey N Cook, Meredith T Lilley, Yuping Song, Caroline F Harlow, Björn E Oskarsson, Katharine A Nicholson, Zbigniew K Wszolek, LaTonya J Hickson, John C O'Horo, Jonathan B Hoyne, Tania F Gendron, James F Meschia, Leonard Petrucelli
Serum neurofilament light protein correlates with unfavorable clinical outcomes in hospitalized patients with COVID-19. Science translational medicine 13 (602) (2021)
Mercedes Prudencio, Hector Garcia-Moreno, Karen R Jansen-West, Rana Hanna Al-Shaikh, Tania F Gendron, Michael G Heckman, Matthew R Spiegel, Yari Carlomagno, Lillian M Daughrity, Yuping Song, Judith A Dunmore, Natalie Byron, Björn E Oskarsson, Katharine A Nicholson, Nathan P Staff, Sorina Gorcenco, Andreas Puschmann, João M Lemos, Cristina Januário, Mark S LeDoux, Joseph H Friedman, James Polke, Robin Labrum, Vikram G Shakkottai, Hayley S McLoughlin, Henry L Paulson, Takuya Konno, Osamu Onodera, Takeshi Ikeuchi, Mari Tada, Akiyoshi Kakita, John D Fryer, Christin Karremo, Inês Gomes, John N Caviness, Mark R Pittelkow, Jan O Aasly, Ronald F Pfeiffer, Venka Veerappan, Eric R Eggenberger, William David Freeman, Josephine F Huang, Ryan J Uitti, Klaas J Wierenga, Iris V Marin Collazo, Philip Wade Tipton, Jay A van Gerpen, Marka van Blitterswijk, Guojun Bu, Zbigniew K Wszolek, Paola Giunti, Leonard Petrucelli
Toward allele-specific targeting therapy and pharmacodynamic marker for spinocerebellar ataxia type 3. Science translational medicine 12 (566) (2021)
Tania F Gendron, Mohammed K Badi, Michael G Heckman, Karen R Jansen-West, George Koshy Vilanilam, Patrick W Johnson, Alexander R Burch, Ronald L Walton, Owen A Ross, Thomas G Brott, Timothy M Miller, James D Berry, Katharine A Nicholson, Zbigniew K Wszolek, Björn E Oskarsson, Kevin Navin Sheth, Lauren Hachmann Sansing, Guido J Falcone, Brett L Cucchiara, James F Meschia, Leonard Petrucelli
Plasma neurofilament light predicts mortality in patients with stroke. Science translational medicine 12 (569) (2021)
Jessica A Bush, Haruo Aikawa, Rita Fuerst, Yue Li, Andrei Ursu, Samantha M Meyer, Raphael I Benhamou, Jonathan L Chen, Tanya Khan, Sarah Wagner-Griffin, Montina J Van Meter, Yuquan Tong, Hailey Olafson, Kendra K McKee, Jessica L Childs-Disney, Tania F Gendron, Yong-Jie Zhang, Alyssa N Coyne, Eric T Wang, Ilyas Yildirim, Kye Won Wang, Leonard Petrucelli, Jeffrey D Rothstein, Matthew D Disney
Ribonuclease recruitment using a small molecule reduced c9ALS/FTD r(G4C2) repeat expansion in vitro and in vivo ALS models. Science translational medicine 13 (617) (2021)
Casey N Cook, Yanwei Wu, Hana M Odeh, Tania F Gendron, Karen R Jansen-West, Giulia Del Rosso, Mei Yue, Peizhou Jiang, Edward Gomes, Jimei Tong, Lillian M Daughrity, Nicole M Avendano, Monica Castanedes Casey, Wei Shao, Björn E Oskarsson, Giulio S Tomassy, Alexander McCampbell, Frank Rigo, Gourisankar Ghosh, James Shorter, Yong-Jie Zhang, Leonard Petrucelli
C9orf72 poly(GR) aggregation induces TDP-43 proteinopathy. Science translational medicine 12 (559) (2021)
Yong-Jie Zhang, Lin Guo, Patrick K Gonzales, Tania F Gendron, Yanwei Wu, Karen Jansen-West, Aliesha D O'Raw, Sarah R Pickles, Mercedes Prudencio, Yari Carlomagno, Mariam A Gachechiladze, Connor Ludwig, Ruilin Tian, Jeannie Chew, Michael A DeTure, Wen-Lang Lin, Jimei Tong, Lillian M Daughrity, Mei Yue, Yuping Song, Jonathan W Andersen, Monica Castanedes Casey, Aishe Kurti, Abhishek Datta, Giovanna Antognetti, Alexander McCampbell, Rosa Rademakers, Björn E Oskarsson, Gourisankar Ghosh, Martin Edward Kampmann, Michael Emmerson Ward, John D Fryer, Christopher D Link, James Shorter, Leonard Petrucelli
Heterochromatin anomalies and double-stranded RNA accumulation underlie C9orf72 poly(PR) toxicity. Science (New York, N.Y.) 363 (6428) (2019)
Tania F Gendron, Jeannie Chew, Jeannette N Stankowski, Lindsey R Hayes, Yong-Jie Zhang, Mercedes Prudencio, Yari Carlomagno, Lillian M Daughrity, Karen Jansen-West, Emilie A Perkerson, Aliesha D O'Raw, Casey Cook, Luc Pregent, Veronique V Belzil, Marka van Blitterswijk, Lilia J Tabassian, Chris W Lee, Mei Yue, Jimei Tong, Yuping Song, Monica Castanedes Casey, Linda Rousseau, Virginia Phillips, Dennis W Dickson, Rosa Rademakers, John D Fryer, Beth K Rush, Otto Pedraza, Ana M Caputo, Pamela Desaro, Carla Palmucci, Amelia Robertson, Michael G Heckman, Nancy N Diehl, Edythe Wiggs, Michael Tierney, Laura Braun, Jennifer Farren, David Lacomis, Shafeeq Ladha, Christina N Fournier, Leo F McCluskey, Lauren B Elman, Jon B Toledo, Jennifer D McBride, Cinzia Tiloca, Claudia Morelli, Barbara Poletti, Federica Solca, Alessandro Prelle, Joanne Wuu, Jennifer Jockel-Balsarotti, Frank Rigo, Christine Ambrose, Abhishek Datta, Weixing Yang, Denitza Raitcheva, Giovanna Antognetti, Alexander McCampbell, John C Van Swieten, Bruce L Miller, Adam L Boxer, Robert H Brown, Robert Bowser, Timothy M Miller, John Q Trojanowski, Murray Grossman, James D Berry, William T Hu, Antonia Ratti, Bryan J Traynor, Matthew D Disney, Michael Benatar, Vincenzo Silani, Jonathan D Glass, Mary Kay Floeter, Jeffrey D Rothstein, Kevin B Boylan, Leonard Petrucelli
Poly(GP) proteins are a useful pharmacodynamic marker for C9ORF72-associated amyotrophic lateral sclerosis. Science translational medicine 9 (383) (2017)