Blood M2-like Monocyte Polarization Is Associated with Calcific Plaque Phenotype in Stable Coronary Artery Disease: A Sub-Study of SMARTool Clinical Trial.
Silverio SbranaAntonella CecchettiniLuca BastianiNicoletta Di GiorgiAnnamaria MazzoneElisa CeccheriniFederico VozziChiara CaselliDanilo NegliaAlberto ClementeArthur J H A ScholteOberdan ParodiGualtiero PelosiSilvia RocchiccioliPublished in: Biomedicines (2022)
The association between DCV and M2-like phenotypic polarization of circulating monocytes indicates that plaque macro-calcification in stable CAD may be partly modulated by an anti-inflammatory monocyte functional state, as evidenced by cell membrane receptor patterns.
Keyphrases
- coronary artery disease
- dendritic cells
- clinical trial
- anti inflammatory
- percutaneous coronary intervention
- peripheral blood
- coronary artery bypass grafting
- cardiovascular events
- endothelial cells
- chronic kidney disease
- study protocol
- aortic stenosis
- randomized controlled trial
- immune response
- open label
- phase ii
- double blind
- acute coronary syndrome
- left ventricular
- transcatheter aortic valve replacement