Patient-reported quality-of-life outcomes after de-escalated chemoradiation for human papillomavirus-positive oropharyngeal carcinoma: Findings from a phase 2 trial.
John V HegdeNarek ShaverdianMegan E DalyCarol FelixDeborah L WongMichael H RosoveJordan H GarstPin-Chieh WangDarlene VeruttipongShyam RaoRuben C FragosoJonathan W RiessMichael L SteinbergAllen M ChenPublished in: Cancer (2017)
This de-escalation regimen achieved QOL outcomes that were favorable compared with historical controls. These results serve as powerful evidence that ongoing de-escalation efforts lead to tangible gains in function and QOL. Cancer 2018;124:521-9. © 2017 American Cancer Society.