Quantitative proteomic analysis of human peripheral nerves from subjects with type 2 diabetes.

Erik IsingEmma ÅhrmanNiels O B ThomsenKarl-Fredrik ErikssonJohan Malmstöm Lars B Dahlin

Published in: Diabetic medicine : a journal of the British Diabetic Association (2021)

This feasibility study shows, for the first time, that the use of quantitative mass spectrometry enables quantification of proteins from nerve biopsies from subjects with and without type 2 diabetes, which may aid in finding biomarkers of importance to DPN development.

Keyphrases

type diabetes
mass spectrometry
high resolution
endothelial cells
liquid chromatography
cardiovascular disease
induced pluripotent stem cells
pluripotent stem cells
high performance liquid chromatography
insulin resistance
peripheral nerve